Lab Focus: Biological Engineering
Project Name: Understanding Immune Cell Migration in In Vitro Cancer Models
Project Description: Immunotherapy is the most recent breakthrough in cancer treatment. However, it is not successful in all patients. Biomarkers predicting response to therapy have not been established yet, so we are using in vitro systems to model interactions between cancer cells and immune cells. Two-dimensional and unique 3-dimensional microfluidic cell culture methods will be used to quantify migration of T cells toward several cancer cell lines. The student will be introduced to several techniques including microfluidic device fabrication, cell culture, immunostaining, and fluorescent microscopy.
Cynthia Hajal – PhD Candidate
- Vascular Models
Sarah Shelton – PhD
- Cancer Models