All-EBICS Journal Club

All-EBICS Tutorial Journal Clubs.

The research landscapes in all the fields that contribute to EBICS are rapidly evolving, and some of the fields may be entirely new to students (and even some faculty) entering the EBICS program. We therefore initiated a running series of approximately monthly “expert tutorial/journal club” sessions, held by interactive webcast (BlueJeans: cloud based video-conferencing service) in which a faculty member chooses 2-3 high-impact, recent research papers to review in a field, and provides background reading (reviews and older research papers) ahead of time, and then during the presentation, begins with a structured tutorial of the history and state of the art in the field for context before leading discussion and analysis of the research papers.  This format allows students to get a quick but highly organized synopsis of the important work and approaches in EBICS and become familiar with literature crucial for their professional development.  Each session is held in duplicate on different days/times so that all students have a chance to participate regardless of their schedules, and students are highly interactive with questions during the discussion. EBICS faculty participates in these sessions along with students, as a means of having the entire program gain a common ground of understanding.  

Journal Club Archive Articles

December 2016 - Presenter: Prof. Laurie Boyer (MIT)

  • Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types 
  • Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation

Missed it? Listen to the discussion now!

 

September 2016 - Presenter: Prof. Taher Saif (UIUC)

  • More is Different

 

April 2016 - Presenter: Prof. Yuhong Fan (GT)

  • Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity
  • Heterogeneity in Oct4 and Sox2 targets biases cell fate in 4-cell mouse embryos
  • Long-lived binding of Sox2 to DNA predicts cell fate in the four-cell mouse embryo

 

May 2015 - Presenter: Prof. Steve Stice (UGA)

  • An FDA perspective on preclinical development of cell-based regenerative medicine products
  • Hope for regenerative treatments: toward safe transplantation of human pluripotent stem-cell-based therapies
  • The global intellectual property landscape of induced pluripotent stem cell technologies

 

April 2015 - Presenter: Prof. Calin Belta (BU)

  • A Formal Methods Approach to Pattern Recognition and Synthesis in Reaction Diffusion Systems 
  • Statistical Pattern Recognition: A Review
  • SpaTeL: A Novel Spatial-Temporal Logic and Its Applications to Networked Systems

 

December 2014 - Presenter: Prof. Martha Gillette (UIUC)

  • Converting Human Skin Cells to Neurons: A New Tool to Study and Treat Brain Disorders?
  • Induced Neuronal Cells: How to Make and Define a Neuron
  • Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCLI
  • Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts

 

October 2014 – Presenter: Prof. Roger Kamm (MIT)

  • The Effect of Endothelial Cells on hESC-derived pancreatic progenitors in a 3D environment
  • A Three-Dimensional In Vitro Model of Tumor Cell Intravasation

 

May 2014 - Presenters: Prof. Hyunjoon Kong (UIUC) and Prof. Taher Saif (UIUC)

  • Complexity in Biomaterials for Tissue Engineering
  • Mechanotransduction in Development: A Growing Role for Contractility
  • Growth Factors, Matrices, and Forces Combine and Control Stem Cells
  • Manipulation of 3D Cluster Size and Geometry by Release from 2D Micropatterns

 

February 2014 - Presenter: Prof. Ron Weiss (MIT)

  • Synthetic Biology in Mammalian Cells: Next Generation Research Tools and Therapeutics
  • Programmable Single-Cell Mammalian Biocomputers

 

December 2013 - Presenter: Prof. Todd McDevitt (Gladstone Institute)

  • Canonical Wnt Signals Combined with Suppressed TGF/BMP Pathways Promote Renewal of the Native Human Colonic Epithelium
  • Cell Organization in the Colonic Crypt: A Theoretical Comparison of a Pedigree and Niche Concepts
  • Capture and 3D Culture of Colonic Crypts and Colonoids in a Microarray Platform
  • Niche-Independent High-Purity Cultures of Lgr5+ Intestinal Stem Cells and Their Progeny

 

November 2013- Presenter: Prof. Stanislav Shvartsman (Princeton)

  • Self-Formation of Layered Neural Structures in 3D Culture of ES Cells
  • In Vitro Organogenesis in three dimensions: self-organising stem cells
  • Cytosystems Dynamics in Self-Organization of Tissue Architechture
  • Grow Your Own Eye
  • Self-Formation of Optic Cups ad Storable Stratified Neural Retina fro Human ESCs
  • Modeling Cell Proliferation for Stimulating three-dimensional tissue
  • Self-formation of Functional Adeno-Hypophysis in Three-Dimensional Culture

 

October 2013 - Presenter: Prof. Stanislav Shvartsman (Princeton)

  • Cerebral Organoids in a Dish: Progress and Prospects
  • SnapShot: Directed Differentiation of Pluripotent Stem Cells
  • Polarity in Mammalian Epithelial Morphogenesis
  • Cerebral Organoids Model Human Brain Development and Microcephaly