The goals of the Motile Bots working group are to design, construct, and analyze a family of biobots that emerge from interactions between cells and elementary engineered scaffolds. Their objective functions are walking and swimming in fluids. The cells involved are muscle, neurons and endothelial cells. These motile bots will ultimately have intelligence, as the neurons will stimulate the muscle cells on an on-demand basis by sensing the environment. Another goal is to use the biobot platforms to study emergent properties of neuron cell clusters, cross talk between neurons and muscle, and neuromuscular junctions.
Computational predictions of cysteine cathepsin-mediated fibrinogen proteolysis.. Protein Sci. 27(3):714-724.. 2018.