Objective: Develop motile machines involving differentiated and trained neurons, muscle, and vasculature. The machines will have sensing and actuation abilities with elementary logic. They can be stimulated by light or electric fields, chemical gradients, or they can be self-propelled. Performance improvement or optimization can be achieved through training or adaptation.
Hypothesis: Such semi-intelligent machines will emerge through cell-cell and cell-scaffold interactions under the guidance of specific chemical, mechanical, and electrical cues.