Dr. Robert Langer
MIT Department of Chemical Engineering
"Engineering of Integrated Materials and Cell Based Systems"
I will start by discussing how I - as a chemical engineer - initially got involved in the interface between biology and engineering, which would lead to the isolation of the first angiogenesis inhibitors and the development of controlled release systems for macromolecules. I will then cover the engineering of novel microelectronic systems. Such systems have the ability to sense levels of drugs or other substances in blood. They can also secrete drugs into the bloodstream. Next, the possibility of creating cell based tissues and organs - and the challenges associated with that - will be discussed. Finally, the development of new high-throughput, polymer-based tools that can control the differentiation and growth of stem cells and other cells will be examined.