"BioMEMS and Biofabrication for Development of Cellular Systems"
Development of cellular systems and biological machines will require technologies for the characterization, manipulation, and arrangement of cells. Microfabrication-inspired approaches can play an important role towards achieving these goals. In this talk, we will present an overview of our work relevant to the NSF STC (Emergent Behavior of Integrated Cellular Systems). We will summarize our recent developments using micro-mechanical sensors for characterization of mass and growth of single adherent cells, 2- and 3-D patterning of cells (fibroblasts, muscle, and neurons) for applications in angiogenesis and tissue engineering, and fabrication of hybrid cell-polymer structures as building blocks for biological machines.